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Important Safety Information

Mechanism of Action Semaglutide is a synthetic glucagon-like peptide-1 (GLP-1) receptor agonist that belongs to a class of drugs called incretin mimetics. Incretins are a type of hormone that stimulate a decrease in blood glucose levels, such as GLP-1 that binds to and activates the GLP-1 receptor. GLP-1 works to regulate ones appetite and caloric intake, and the GLP-1 receptor is present in several areas of your body, including areas in your brain responsible for appetite regulation. Semaglutide, as an agonist, binds to the GLP-1 receptor and works to lower blood glucose by stimulating insulin secretion and to inhibit glucagon release.
Adverse Reactions Semaglutide is associated with GI adverse reactions, including nausea, diarrhea, vomiting, constipation, abdominal pain, dyspepsia, abdominal distention, eructation, flatulence, gastroenteritis, and gastroesophageal reflux disease. It has also been associated with causing headache, fatigue, dizziness, and hypoglycemia in patients with type 2 diabetes. Please discuss with your physician the contraindications and other warning and precautions before starting Semaglutide.

Important Safety Information

Mechanism of Action Liraglutide is an analog of human GLP-1, and acts as a GLP-1 receptor agonist. Liraglutide increases intracellular cyclic AMP (cAMP) leading to insulin release in the presence of elevated glucose concentrations.

Adverse Reactions The most common Liraglutide side effects are nausea, vomiting, diarrhea, constipation and headache. Although rare, Liraglutide can cause serious side effects. These include pancreatitis, gallbladder disease, and kidney problems. Please discuss with your physician the contraindications and other warnings and precautions before starting Liraglutide.


Important Safety Information

Mechanism of Action Tirzepatide is both a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist. It selectively binds to and activates the GIP and GLP-1 receptors, the targets for native GIP and GLP-1 hormones. GIP and GIP-1 are hormones that are primarily released from the body’s small intestine that enhances the release of insulin following the consumption of food. Both of these hormones are known as incretins, with tirzepatide belonging to a class of drugs known as incretin mimetics. Tirzepatide works by directly activating GIP and GLP-1 pathways to help regulate blood sugar.
Adverse Reactions The most common side effects of tirzepatide include nausea, diarrhea, decreased appetite, vomiting, constipation, indigestion, and stomach (abdominal) pain. These are not all the possible side effects of Tirzepatide. Please discuss with your physician the contraindications and other warnings and precautions before starting tirzepatide.
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